butabarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of CYP3A4 inducers may possibly reduce sufentanil ranges and efficacy, possibly precipitating withdrawal syndrome in people that have designed Bodily dependence to sufentanil. Discontinu… Read More